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KMID : 0378019710140010070
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New Medical Journal
1971 Volume.14 No. 1 p.70 ~ p.76
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Experimental Studies on the Epiphyseal Plate Following Autigenous and Homogenous Bone Transplatation
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石世一/Suk, Se Il
奇正一/韓文植/Kee, Jung Ihl/Hahn, Moon Sik
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Abstract
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Clinical attempts on the epiphyseal transplantation have been reported for last few decades, even supporting experimental studies have not been performed concerning to transplantation of the massive autogenous and homogenous bone including epiphyseal plate.
The authors have observed histologically on the changes of the epiphyseal growth cartilage for the interval of 3 days to 12 weeks following experimental surgery, by which the distal femoral metaphysis were resected at the point of 1 cm above the epiphyseal line with 84 immature rabbits divided into 3 groups for control, autogenous and homogenous transplantation.
In the autogenous transplantion, the epiphyseal cartilage revealed growing up to 5 weeks similar to control group follwed by the tendency of increased degenerative changes, calcification and finally bony union between epiphysis and metaphysis at 12 weeks after transplantation. The homogenous transplantation group also revealed similar picture to the autogenous graft until 5 weeks, followed by rapid necrosis with cessation of growth and completely disappeared at 8 weeks following surgery.
It is believed that the changes following massive autogenous transplantation might be due to interruption of vascular channel and the homogenous transplantation with additional rejection phenomenon from trans￢plantation immunity
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